Skip to content

Effectiveness of uterine local injury in improving pregnancy in unexplained infertility

To compare the effect of endometrial local injury on frequency of pregnancy in couples with unexplained infertility by control group

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012082510657N1
Enrollment
234
Registered
2012-11-26
Start date
2010-01-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility, unspecified

Interventions

Intervention 1: All the patients will undergo optimal superovulation by clomiphene-citrate (Razac Drug Laboratory,Tehran,Iran ) orally administered 100 milligram/day from day 3 to day 7 of the cycle a
Treatment - Other
Treatment - Drugs
All the patients will undergo optimal superovulation by clomiphene-citrate (Razac Drug Laboratory,Tehran,Iran ) orally administered 100 milligram/day from day 3 to day 7 of the cycle and HMG-Merional

Sponsors

Vice chancellor for research; Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
23 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1) Couples with no obvious reasons for infertility(normal routine infertility evaluation evaluation of infertility are normal) referring to Infertility Research Center in Shiraz, Iran were included in this study. 2) infertile women who were in their 23-35 years of age, 3) body mass index between 18 and 25 (kg/m2), 4)anti-mullerian hormone more than 1 µg/l ,5) follicle stimulating hormone levels less than 10 mIU/ml on the third day of cycle, 6) at least 10-12 follicles in AFC count and 7) couples receiving no drugs for infertility at least for three previous months . The exclusion criteria were 1) women younger than 23 or older than 35, as well as those (each of the infertile partner) who were cigarette smoker, and/or alcohol abuser.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pregnancy. Timepoint: two weeks after the missed period. Method of measurement: measuring level of blood Beta human chorionic gonadotropin by ELISA.

Secondary

MeasureTime frame
Clinical pregnancy. Timepoint: 4 weeks after the missed period. Method of measurement: detecting of intrauterine sac by vaginal sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNajmeh Maharlouei

Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

najmeh.maharlouei@gmail.com+98 71 1230 2799

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026