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Effect of N-acetyl cysteine in reducing the injuries caused by exhaustive exercise

Evaluation of the effect of oral consumption of N-acetyl Cysteine in reducing the injuries caused by a single bout of exhaustive exercise in untrained young subjects

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201208238129N2
Enrollment
30
Registered
2013-05-10
Start date
2013-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oxidative stress injuries. -

Interventions

Intervention 1: Intervention group:effervescent tablets of N-acetyl cysteine as 4 times starting 24 hours before the trial. Intervention 2: placebo group: dextrose %3 as dissolved in water.
Prevention
Placebo
Intervention group:effervescent tablets of N-acetyl cysteine as 4 times starting 24 hours before the trial
placebo group: dextrose %3 as dissolved in water

Sponsors

Deputy of Research,Bushehr University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
21 Years to 25 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: participants aged between 21 and 25; either sex; having Vo2 max between 35 to 40 ml/kg/min ; and living in the same dormitory ; all having the same type of food. Exclusion criteria: subjects who were consuming energetic drugs; smokers; those having any type of regular sport activity.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Total antioxidant capacity. Timepoint: Before the consumption of drug; one hour before start of the exercise;Immidiately after exercise;after one at rest hour. Method of measurement: By ELISA method and commercial kits.;C-reactive protein (CRP). Timepoint: Before the consumption of drug; one hour before start of the exercise;Immidiately after exercise;after one at rest hour. Method of measurement: By ELISA method and commercial kits.;Malondealdehyde. Timepoint: Before the consumption of drug; one hour before start of the exercise;Immidiately after exercise;after one at rest hour. Method of measurement: By spectraphothometry.

Secondary

MeasureTime frame
BMI. Timepoint: Before the trial. Method of measurement: weight in kilograms divided by the square of height in meters.;Vo2 max. Timepoint: Before and after the trial. Method of measurement: Cooper Standard Aerobic Test was used.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Movahed

Bushehr University of Medical Sciences

amovahed58@gmail.com, amirali_1957@yahoo.com+98 77 1252 9198

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026