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Comparison effects and Complications of propofol and isoflurane anesthesia for open cholecystectomy

Comparison effects and Complications of propofol and isoflurane anesthesia for open cholecystectomy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120817010617N6
Enrollment
60
Registered
2021-01-13
Start date
2021-01-20
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallstone disease. Disease of gallbladder, unspecified

Interventions

Intervention 1: First Intervention group, Isofluran group: Isofluran 1.5% 1.5MAC inhalation in Anesthesia time. Intervention 2: Second Intervention group, Propofol group: Intravenous propofol infusion

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age between 15 and 80 years old American Society of Anesthesiologists (ASA) Class I & II

Exclusion criteria

Exclusion criteria: History of allergic reaction to these medication Drug abuse Common Cold Heart and Renal diseases, Hypertension Taking tranquilizer medication Not signing informed consent to participate in the study Two failed attempts for Intubation

Design outcomes

Primary

MeasureTime frame
Blood Pressure. Timepoint: Every 5 Minutes from beginning of intervention till the end of surgery. Method of measurement: Manometer.;Heart Rate. Timepoint: Every 5 Minutes from beginning of intervention till the end of surgery. Method of measurement: ECG Monitor.;Awakening time from anesthesia. Timepoint: When patient awakes and obeys. Method of measurement: Clinical Observation (Minutes).;Nausea & Vomiting. Timepoint: After patients awakening In recovery room. Method of measurement: Observe and record in a data form.;Hoarseness. Timepoint: After patients awakening In recovery room. Method of measurement: Observe and record in a data form.;Staying time in recovery room. Timepoint: After patients awakening In recovery room. Method of measurement: clinical, record in a data form.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNader Toofani Shahraki

Zahedan University of Medical Sciences

ntuofanishahraki@gmail.com+98 54 3329 5570

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026