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Effect of dexamethasone on blood glucose concentration

A comparative study on the effect of different doses of dexamethasone on blood glucose concentration in patients undergoing elective abdominal surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120814010599N13
Enrollment
96
Registered
2017-12-21
Start date
2017-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperglycemia due to steroid. Adverse effect of glucocorticoids

Interventions

Intervention 1: Intervention group 1 : . Before the intervention, blood glucose and other basic indicators are checked. 32 patients In a group ,4 mg intravenous dexamethasone is injected at the begin
Prevention
Placebo
Intervention group 1 : . Before the intervention, blood glucose and other basic indicators are checked. 32 patients In a group ,4 mg intravenous dexamethasone is injected at the beginning of the surg
Intervention group 2 : . Before the intervention, blood glucose and other basic indicators are checkedand. 32 patients in the second group, 8 mg dexamethasoneare injected. The drugs are prepared by t
Control group: Before the intervention, blood glucose and other basic indicators are checked. 64 patients in the third group, placebo (normal saline) are injected. . The drugs are prepared by the oper

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: All people who are candidates for abdominal surgery

Exclusion criteria

Exclusion criteria: cardiovascular patients Recent history of steroid use History of allergy to any of the drugs used in the study. pulmonary patients renal patients hepatic patients DM patients

Design outcomes

Primary

MeasureTime frame
Blood glucose levels. Timepoint: After surgery, at 6 hours and 24 hours after administration of dexamethasone or placebo. Method of measurement: Blood glucose is measured using a glucometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPoupak Rahimzadeh

Iran University of Medical Sciences

p-rahimzadeh@tums.ac.ir+98 21 8670 2503

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026