Ulcerative Colitis. Ulcerative colitis
Conditions
Interventions
Intervention 1: Control group 1 included 20 people who are referred for screening with all the features of patients group except history of clinical or colonoscopic bowel disease.Endoscopy and colonos
one from ulcerative tissue, one from normal intestinal tissue and the last one from body of the stomach
Systemic arterial blood gas sampling (ABG) are performed from radial artery after Allen testing.
Diagnosis
Control group 1 included 20 people who are referred for screening with all the features of patients group except history of clinical or colonoscopic bowel disease.Endoscopy and colonoscopy will also a
Control group 2:Ten paraffin wax embedded tissue species from mesenteric ischemia and ten paraffin wax embedded tissue species include infectious colitis entered the study.For this group just tissue
Patients group interventions:
Ten patients with Ulceratve Colitis are selected.Patients should be known case of UC and are diagnosed by clinical symptoms, sigmoidoscopy or colonoscopy findings and p
one from ulcerative tissue, one from normal intestinal tissue and the last one from body of the stomach
Systemic arterial blood gas sampling (ABG) are performed from radial artery after Allen testing
Sponsors
Faculty of Medicine, Tehran University of Medical science, Tehran, Iran
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: We conducted a randomised clinical trial study to assess the role of ischemia in UC. 20 patients with UC, 20 people without any history of bowel disease and ten paraffin wax embedded tissue species from mesenteric ischemia and ten paraffin wax embedded tissue species include infectious colitis entered the study. UC is diagnosed by clinical symptoms, sigmoidoscopy or colonoscopy findings and pathological species on biopsy.1Patients who took NSAIDs, vasodilators, corticosteroids (some studies showed they might affect tissue oxygenation) and patients with past medical history of ischemic heart disease, pulmonary disorders (COPD, asthma), severe anemia and vascular disease ( vasculitis) and Diabetes which can cause tissue hypoxia were excluded. Control group included 10 people who were referred for screening with all the features mentioned above except history of clinical or colonoscopic bowel disease. Both group had the same age, sex and lived in the same height above the sea level.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pericapillary Blood Gas. Timepoint: Before intervention and after intervention. Method of measurement: Laboratory data reports.;SystemicArterial Blood Gas. Timepoint: Before intervention and after intervention. Method of measurement: Laboratory data repots.;Tissue ischemic factors. Timepoint: Just after sampling. Method of measurement: Specila kits. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Masih Ttajdini
Faculty of Medicine, Tehran University of Medical science
Outcome results
None listed