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Effect of adding intravenous immunoglobulin to heparin and aspirin regiment for prevention of reccurent abortion

Effect of adding intravenous immunoglobulin to heparin and aspirin regiment for prevention of reccurent abortion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012081210568N1
Enrollment
68
Registered
2013-03-16
Start date
2011-07-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Abortion. Pregnancy with abortive outcome

Interventions

Intervention 1: in control group treatment is Low Molcular Weight Heparin(noxaparin) 40 mg daily sub cotaneus for 24 weeks And Aspirin 80 mg daily for 37 weeks. Intervention 2: case group treat with I
Treatment - Drugs
in control group treatment is Low Molcular Weight Heparin(noxaparin) 40 mg daily sub cotaneus for 24 weeks And Aspirin 80 mg daily for 37 weeks.
case group treat with IVIG 200 mg/kg mounthly for 24 weeks and Low Molcular Weight Heparin(noxaparin) 40 mg daily sub cotaneus for 24 weeks And Aspirin 80 mg daily for 37 weeks.

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: inclusion criteria: pregnant women with reccurent abortion ( was defined as two or more consecutive fetal losses before the 20th gestational week). exclusion criteria: other couse for abortion such as structural and anatomical disorder; Abnormal result of chromosomal analysis of the couple; using anti coagulant in pregnancy; aspirin sensivity; hypertention; peptic ulcer.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Recurrent abortion. Timepoint: 4th month after intervention. Method of measurement: physical examination.

Secondary

MeasureTime frame
Continue of pregnancy. Timepoint: when pregnancy terminat. Method of measurement: physical exam.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactdr zinab nazari

Mazandaran University of Medical Sciences

zinabnazari@mazums.ac.ir+98 15 1225 2845

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026