Effect of Teucrium polium on oxidative stress indices in young athletes

Effect of Aqueous Extract of Teucrium polium on oxidative stress in young athletes after graded maximal aerobic exercise

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012080610512N1

Enrollment

Registered

2013-02-25

Start date

2011-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oxidative stress. other physical therapy

Interventions

Intervention 1: The subjects in the supplemented group were given prepared aqueous extract of Teucrium polium (125 ml/kg/day), 7 day before of aerobic exercise protocol. Intervention 2: subject in pla

Placebo

The subjects in the supplemented group were given prepared aqueous extract of Teucrium polium (125 ml/kg/day), 7 day before of aerobic exercise protocol

subject in placebo group also received 125 gr/day/kg of placebo 7 day before of aerobic exercise protocol.

Eligibility

Sex/Gender

Male

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Males; young athlethes; aged 18-30years; No current chronic health problems; No consumption of any supplements or steroid anabolic drugs within the past 6 months Exclusion criteria: Smoking; injuries; acute diseases; and uncontrolled intake of any supplement or drugs (during the period).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Oxidative stress indices (MDA, FRAP, SOD, 8-iso-PGF2a ). Timepoint: prior of supplementation, pre exercise, immediately after exercise and 24 h post exercise. Method of measurement: The total antioxidant capacity of plasma was evaluated by applying the FRAP assay (ferric reducing antioxidant power or ferric reducing ability of plasma). Moreover, Plasma malondialdehyde (MDA) concentrations spectrophotometrically were assayed by measurement of thiobarbituric acid reactive substances (TBARS) assay. Serum 8-iso-PG F2a and Superoxide Dismutase (SOD) levels were measured with a commercially available kit.	—

Measure

Time frame

Oxidative stress indices (MDA, FRAP, SOD, 8-iso-PGF2a ). Timepoint: prior of supplementation, pre exercise, immediately after exercise and 24 h post exercise. Method of measurement: The total antioxidant capacity of plasma was evaluated by applying the FRAP assay (ferric reducing antioxidant power or ferric reducing ability of plasma). Moreover, Plasma malondialdehyde (MDA) concentrations spectrophotometrically were assayed by measurement of thiobarbituric acid reactive substances (TBARS) assay. Serum 8-iso-PG F2a and Superoxide Dismutase (SOD) levels were measured with a commercially available kit.

—

Secondary

Measure	Time frame
Lipid profile. Timepoint: prior of supplementation, pre exercise, immediately after exercise and 24 h post exercise. Method of measurement: The lipid profile will determine by serum levels of total cholesterol (TC), high-density cholesterol (HDL-C), low-density cholesterol (LDL-C) and triglycerides (TG) using the enzymatic method.;Homosysteine. Timepoint: prior of supplementation, pre exercise, immediately after exercise and 24 h post exercise. Method of measurement: It determined by ELISA methods with commercial kits.	—

Measure

Time frame

Lipid profile. Timepoint: prior of supplementation, pre exercise, immediately after exercise and 24 h post exercise. Method of measurement: The lipid profile will determine by serum levels of total cholesterol (TC), high-density cholesterol (HDL-C), low-density cholesterol (LDL-C) and triglycerides (TG) using the enzymatic method.;Homosysteine. Timepoint: prior of supplementation, pre exercise, immediately after exercise and 24 h post exercise. Method of measurement: It determined by ELISA methods with commercial kits.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Sirvan Atashak

Department of Physical Education & Sports Science, Azad University, Mahabad Branch, university Stree

s.atashak@iau-mahabad.ac.ir+44 22341002

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026