Fertility outcomes following intrauterine injection of human chorionic gonadotropin (HCG) before embryo transfer

The effects of intrauterine injection of human chorionic gonadotropin ( HCG) before embryo transfer on fertility outcomes in infertile women undergoing Invitro fertilization (IVF).

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201208058469N2

Enrollment

200

Registered

2013-04-15

Start date

2012-11-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. inability to achieve a pregnancy sterility, female NOS

Interventions

Intervention 1: Intrauterine injection of 0.1 cc (500 units) of human chorionic gonadotropin (HCG) (Coracon type, Ferring, Düsseldorf, Germany) before embryo transfer. Intervention 2: No intrauterine

Treatment - Drugs

Treatment - Other

Intrauterine injection of 0.1 cc (500 units) of human chorionic gonadotropin (HCG) (Coracon type, Ferring, Düsseldorf, Germany) before embryo transfer

No intrauterine injection before embryo transfer.

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: All patients younger than 40 years old referred to the infertility clinic of Shariati Hospital and will undergo In vitro fertilization (IVF) for the first time. Exclusion criteria: Patients with endometriosis, azoospermia, patients with uterine fibroids or history of myomectomy, and patients with hydrosalpingitis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: detection of fetal heart rate in trans vaginal sonography.	—

Secondary

Measure	Time frame
Implantation rate. Timepoint: 3 weeks after embryo transfer. Method of measurement: number of gestational sacs in trans vaginal sonography to the number of embryos transferred in each cycle.;Ongoing pregnancy. Timepoint: continuation of pregnancy in 20 weeks. Method of measurement: sonography.;Abortion. Timepoint: before 20 weeks. Method of measurement: sonography.;Multiple pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: more than one sac containing fetal heart in sonography.;Ectopic pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: sonography.	—

Measure

Time frame

Implantation rate. Timepoint: 3 weeks after embryo transfer. Method of measurement: number of gestational sacs in trans vaginal sonography to the number of embryos transferred in each cycle.;Ongoing pregnancy. Timepoint: continuation of pregnancy in 20 weeks. Method of measurement: sonography.;Abortion. Timepoint: before 20 weeks. Method of measurement: sonography.;Multiple pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: more than one sac containing fetal heart in sonography.;Ectopic pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: sonography.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mandana Rashidi Meybodi

Tehran University of Medical Sciences.

dr.mrashidi@hotmail.com+98 21 8822 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026