effectiveness of mutaflor on bowel habit changes in patients affected by Irritable bowl syndrome

comparison of mutaflor effect vs standard treatment on bowel habit changes in patients affected by Irritable bowl syndrome

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012080510503N1

Enrollment

160

Registered

2012-12-03

Start date

2013-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Irritable bowel syndrome. Condition 2: Irritable bowel syndrome. Irritable bowel syndrome with diarrhoea Irritable bowel syndrome without diarrhoea

Interventions

Intervention 1: Patients will take either one capsule MUTAFLOR® (with 2.5–25×109 CFU Escherichia coli Nissle 1917) o.d. for 4 days and there after two capsules MUTAFLOR® o.d. throughout the trial. In

Treatment - Drugs

Patients will take either one capsule MUTAFLOR® (with 2.5–25×109 CFU Escherichia coli Nissle 1917) o.d. for 4 days and there after two capsules MUTAFLOR® o.d. throughout the trial

placebo capsule 1 capsule per day for 4 days then 2 capsules per day for 1 month

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age between 20 to 50; Fulfilled Rome 3 criteria; Tendency to take part in study Exclusion criteria: Usage any of probiotics in a month before study; Pregnancy; Previous abdominal surgery except cholecystectomy and appendectomy; Any active gastrointestinal disease; Cow milk protein allergy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Diarrhea. Timepoint: 1month after intervention. Method of measurement: Integrative Medicine Patient Satisfaction Scale.;Constipation. Timepoint: 1month after intervention. Method of measurement: Integrative Medicine Patient Satisfaction Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHajar Nikbakht

Colorectal Resaerch Center, Rasoulakaram Hospital,Tehran University of Medical Science

Hajarnik@yahoo.com+98 21 6435 2358

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026