Comparative study of the effects of Sevoflurane and Isoflurane on bleeding rate during endoscopic surgery of nasal sinus

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120801010471N3

Enrollment

Registered

2018-08-05

Start date

2016-11-21

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effect of sevoflurane and isoflurane on bleeding rate of functional endoscopic sinus surgery.

Interventions

Intervention 1: 23 patients will be assigned to each group. Continuous clinical monitoring is performed with EKG, Pulse Oximetry, temperature, BP for every 3 minutes and Bispectral Index (A 2000 BIS_X

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Elective surgery Patients between 18 and 60 years old ASA 1,2

Exclusion criteria

Exclusion criteria: BMI=30 Alchohol user Medications that affect MAC Communication problems Fungal sinusitis Nasal polyps greater than 3 (due to increased inflammation and vascularity of the vessels that both cause increasing bleeding in the surgical field and Surgery Grade Score) Substance user

Design outcomes

Primary

Measure	Time frame
Bleeding rate on endoscopic sinus surgery. Timepoint: The measurement of the amount of bleeding is evaluated with the mass of used sterilized gases using a calibrated scale each day and the amount of blood accumulated in the suction in cc .and after 60 minutes through Grade Score, the surgeon also evaluates the amount of bleeding during the surgery. Method of measurement: Grade Assessment : 0 = No bleeding (Cadaveric conditions). 1= Slight bleeding - no suctioning required. 2= Slight bleeding - occasional suctioning required.3 = light bleeding - frequent suctioning required; bleeding threatens surgical field a few seconds after suction is removed.	—

Measure

Time frame

Bleeding rate on endoscopic sinus surgery. Timepoint: The measurement of the amount of bleeding is evaluated with the mass of used sterilized gases using a calibrated scale each day and the amount of blood accumulated in the suction in cc .and after 60 minutes through Grade Score, the surgeon also evaluates the amount of bleeding during the surgery. Method of measurement: Grade Assessment : 0 = No bleeding (Cadaveric conditions). 1= Slight bleeding - no suctioning required. 2= Slight bleeding - occasional suctioning required.3 = light bleeding - frequent suctioning required; bleeding threatens surgical field a few seconds after suction is removed.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMilad Masaeli

Sanandaj University of Medical Sciences

drmilmas@yahoo.com+98 87 3361 1231

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026