Skip to content

antiplatelet effects of garlic

comprasion of antiplatelet activity of garlic tablets with cardioprotective dose of aspirin (80mg/day)in healthy volunteers

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012073110453N1
Enrollment
62
Registered
2014-09-26
Start date
2014-08-24
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

agents affecting blood constituents. Other and unspecified agents affecting blood constituents

Interventions

Intervention 1: garlic 1250mg one tablet a day for 30 days. Intervention 2: garlic(1250mg) 2 tablets a day for 30 days. Intervention 3: 3 tablets(1250 mg) garlic a day for 30 days.
Treatment - Drugs
garlic 1250mg one tablet a day for 30 days
garlic(1250mg) 2 tablets a day for 30 days
3 tablets(1250 mg) garlic a day for 30 days

Sponsors

Pharmaceutical Siences Reseaserch
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Exclusion criteria applied to individuals who had cardiovascular disease, been using aspirin, clopidogrel and nonsteroidal anti inflammatory drugs ( NSAIDS) in the last 2 weeks ago , thrombocytopenia(platelet<100 × 10 3 platelets /mm3 ), anemia(hemoglobin<10g/dl),abnormal lipid profile[total chlosterol = 200 mg/dl , LDL-C =100mg/dl , TG = 200 mg/dl HDL= 45 mg/dl(male) and = 55 mg/dl(female) ], Diabetes mellitus (FBS = 126 mg/ dl confirmed by repeating the test), and renal failure[Serum creatinine = 2mg/dl (female) and Serum creatinine=2.5 mg/dl (male)] inclusion criteria : 62 healthy individuals(non diabetic ? normal lipid profile ? without any cardiovascular disease and coagulation disordes ?non used aspirin, clopidogrel and nonsteroidal anti inflammatory drugs ( NSAIDS) in the last 2 weeks ago aged 20-50 years old were enrolled in this clinical trial.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Platelet aggregation. Timepoint: 3 months. Method of measurement: Light transmission aggregometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojtaba Shafikhani

Shiraz University Of Medical Sciences

mshafikhan@sums.ac.ir+98 71 1727 4596

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026