Skip to content

The effect of taurine in reducing the incidence of ventilator-associated pneumonia

Evaluating the effectiveness of taurine in reducing the incidence of ventilator-associated pneumonia inchildren undergoing mechanical ventilation in the pediatric intensive care unit of Shiraz Namazi Hospital arandomized, double-blind clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120731010453N4
Enrollment
72
Registered
2023-06-29
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator-associated pneumonia. Ventilator associated pneumonia

Interventions

Intervention 1: Intervention group: Patients receive taurine in the amount of 30 mg/kg in the form of 250 mg capsules (in two divided doses) (from Allmax Nutrition Company) until they are hospitalized

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Months to 15 Years

Inclusion criteria

Inclusion criteria: Willingness to participate in the study and complete the ethical consent form by the parents. All children aged 3 months to 15 years who need mechanical ventilation for more than 48 hours.

Exclusion criteria

Exclusion criteria: Malignancy, AIDS Patients with heart failure Age less than three months Cystic fibrosis patients

Design outcomes

Primary

MeasureTime frame
The incidence of ventilator-associated pneumonia. Timepoint: During the intubation period of the patient in the intensive care unit. Method of measurement: Based on the criteria of ventilator-associated pneumonia (doctor's clinical suspicion, patient's tests, patient's radiograph, and culture results).

Secondary

MeasureTime frame
The incidence of septic shock. Timepoint: As long as the patient is in the intensive care unit. Method of measurement: Diagnosis and confirmation by the doctor.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasrin Shirzad yazdi

Shiraz University of Medical Sciences

ny.shirzad@yahoo.com+98 71 3627 0861

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026