Diabetic retinopathy. Diabetic retinopathy
Conditions
Interventions
Intervention 1: In group Avastin: Intravtreal Avastin 1.25 mg will be injected and this injection will be repeated when the central macular thickness is more than 300 µm. Intervention 2: In group vitr
Treatment - Drugs
Treatment - Surgery
In group Avastin: Intravtreal Avastin 1.25 mg will be injected and this injection will be repeated when the central macular thickness is more than 300 µm.
In group vitrectomy: patients will undergo a deep vitrectomy (pars planavitrectomy) surgery.
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: to have diabetic retinopathy; to have central macular thickness more than 300 µm; to have visual acuity between 20/40 and 20/250 and without a high degree refractive error. Exclusion criteria: patients with HbA1C=10 and/or DBP=100 and hyperlipidemia; patients with one eye; patients with any kind of prior intraoccular surgery; patients with prior administration of Avastin; Glaucoma patients and patients with ischemic maculopathy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Central macular thickness. Timepoint: Before the intervention ad 1.5, 3, 4 an 6 months after the intervention. Method of measurement: Occular coherence tumography.;Visual acuity. Timepoint: Before the intervention ad 1.5, 3, 4 an 6 months after the intervention. Method of measurement: using ETDRS chart. | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications. Timepoint: Before the intervention ad 1.5, 3, 4 an 6 months after the intervention. Method of measurement: using slit lamp. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBehrooz Rahimloo
Tabriz University of Medical Sciences
Outcome results
None listed