Comparison of high and low doses of captopril in congestive heart failure (CHF) with left to right shunt

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012072910441N1

Enrollment

Registered

2013-01-11

Start date

2011-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital heart disease. Congenital malformation of cardiac chambers and connections, unspecified

Interventions

Intervention 1: captopril, 0.03mg/kg for 7 days. Intervention 2: Captopril, 0.3mg/kg for 7 days.

Treatment - Drugs

captopril, 0.03mg/kg for 7 days

Captopril, 0.3mg/kg for 7 days

Eligibility

Sex/Gender

All

Age

1 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: congenital heart disease with left to right shunt. Exclusion criteria: Trisomy 21, congenital anomalies including cleft lip and cleft palate esophageal atresia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The effect of captopril. Timepoint: The first, third and 7th day of treatment. Method of measurement: Rose score, Echocardiography.	—

Secondary

Measure	Time frame
Serum Renin and Aldostron. Timepoint: The 7th day. Method of measurement: Renin and Aldostron level and Echocardiography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Saeed Alinejad

Shiraz university of medical sciences

salinejad@sums.ac.ir+98 71 1612 5481

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026