Effects of vitamin D and calcium supplementation in type 2 diabetic patient

Effects of vitamin D and calcium supplementation on inflammatory biomarkers and adipocytokins in patients with type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012072910433N1

Enrollment

120

Registered

2012-08-19

Start date

2012-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: 50000 IUvitamin D3 per week plus calcium placebo for 8 weeks. Intervention 2: 1000 mg calcium carbonate per day plus vitamin D3 placebo for 8 weeks. Intervention 3: 50000 IU vitamin D3

Placebo

1000 mg calcium carbonate per day plus vitamin D3 placebo for 8 weeks

50000 IU vitamin D3 per week plus 1000 mg calcium carbonate per day for 8 weeks

vitamin D3 and calcium placebos for 8 weeks

50000 IUvitamin D3 per week plus calcium placebo for 8 weeks

Eligibility

Sex/Gender

All

Age

30 Years to 149 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: more than 30 years old; not pregnant; do not use any tobacco products; do not inject insulin; have no history of renal failure, cancer, liver diseases, thyroid diseases or any other inflammatory diseases; not using corticosteroids; have not more than 4 kilograms weight change during last 3 months; not consuming any kinds of vitamin D or calcium supplement during last 8 weeks. Exclusion Criteria: Pregnancy; Allergy, trauma or surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Inflammatory Biomarkers. Timepoint: at baseline and after 8 weeks of intervention. Method of measurement: Blood sample and standard methods.;Adipocytokins including Adiponectin and Leptin. Timepoint: at baseline and after 8 weeks of intervention. Method of measurement: Blood sample and standard methods.	—

Secondary

Measure	Time frame
Antropometric Measurments( height, weight,hip and waist circumferences). Timepoint: at the baseline and after 8 weeks of intervention. Method of measurement: height, hip and waist circumferences in cm and weight in kg by standard methods.;Blood pressure. Timepoint: at the baseline and after 8 weeks of intervention. Method of measurement: mmHg.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarjan Tabesh

Isfahan University of Medical Science

tabesh@hlth.mui.ac.ir+98 913 166 4159

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026