Effect of dexamethasone on post-operative pain in laparoscopic cholecystectomy

Effect of single dose intravenous dexamethasone on post-operative pain in patients undergoing laparoscopic cholecystectomy in Razi hospital during 2012

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012072810424N1

Enrollment

122

Registered

2013-02-27

Start date

2012-05-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystitis. Cholecystitis, unspecified

Interventions

Intervention 1: Case group: Intravenous administration of 8 mg single dose dexamethasone during induction of anesthesia. Intervention 2: Control group: Intravenous administration of 2 ml of normal sal

Treatment - Drugs

Placebo

Case group: Intravenous administration of 8 mg single dose dexamethasone during induction of anesthesia.

Control group: Intravenous administration of 2 ml of normal saline during induction of anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Candidates of laparoscopic cholecystectomy that are 18 to 60 years old. Exclusion criteria: Patients younger than 18 or elder than 60 years old; Renal failure; Hepatic failure; History of gastric/duodenal ulcers; Sensitivity to glucocorticoid(s); Those under treatment with glucocorticoids and/or immunosuppressive agents.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post-operative pain. Timepoint: In recovery, 2 hours post-op, 6 hours post-op, 12 hours post-op, 24 hours post-op. Method of measurement: Visual Analogue Scale (VAS).	—

Secondary

Measure	Time frame
N/A. Timepoint: N/A. Method of measurement: N/A.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Babak Masoudrad

Jondishapour University of Medical Sciences

masoudrad.b@ajums.ac.ir; b_m_rad@yahoo.com+98 61 1222 2922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026