Investigating CPAP in Treatment of RDS

Comparison of Ventilators Work of Breath Based on Constant flow nasal CPAP through Pressure Limited and Electronic Feedback Pressure Control Mechanisms in the Treatment of Respiratory Distress Syndrome in Neonates Weighing 1000 grams

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120728010430N8

Enrollment

Registered

2019-05-12

Start date

2015-08-01

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory distress syndrome of newborn. Respiratory distress syndrome of newborn

Interventions

Intervention 1: Control group: Neonates in PL-nCPAP group were supported with nCPAP respiratory support using Nasal prong Argyle (Covidien, Mansfield, USA) with the aid of Christina ventilator (Stepha

Eligibility

Sex/Gender

All

Age

1 Days to No maximum

Inclusion criteria

Inclusion criteria: neonates weighing 1000 grams with respiratory distress syndrome (Tachypnea, Intercostal retraction, nasal flaring, granting, needing inspired oxygen fraction higher than 21%)

Exclusion criteria

Exclusion criteria: congenital anomaly and perinatal asphyxia (5-minute apgar score between 0 and 3, umbilical cord ph less than 7 and umbilical cord bicarbonate less than 12 mEq/Lit)

Design outcomes

Primary

Measure	Time frame
The average Work of Breath in PC- nCPAP and PL- nCPAP. Timepoint: Every 6 hours. Method of measurement: expiratory tidal volume multiplied by dynamic pressure.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Sadeghnia

Esfahan University of Medical Sciences

asadeghnia@gmail.com+98 31 3335 1777

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026