Comparsion two anesthetic drugs (thioental and propofol) on heart rate and blood pressure changes

Comparison of Propofol and Thiopental on hemodynamic in general anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012072510340N3

Enrollment

150

Registered

2012-07-28

Start date

2010-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia.

Interventions

Intervention 1: In the first group thiopental (5 mg/kg bolus injection) before general anesthesia. Intervention 2: In the second group propofol (2 mg/kg bolus injection) before general anesthesia.

Treatment - Drugs

In the first group thiopental (5 mg/kg bolus injection) before general anesthesia

In the second group propofol (2 mg/kg bolus injection) before general anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Patients between 18 to 70 years old with lower limb fracture with ASA class I/II exclusion criteria:All patients with a history of systemic disease (cardiovascular, respiratory, hypertension, diabetes, etc.)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Hemodynamic changes(blood presure and heart rate). Timepoint: during surgery. Method of measurement: monitoring vehicle.	—

Secondary

Measure	Time frame
Nausea and vomoting. Timepoint: After general anesthesia in recovery. Method of measurement: The patient's record.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKazem Kazem Nejad

Golestan University of Medical Siences

kazemnejad1341@yahoo.com+98 17 1442 1651

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026