Keratoconus. keratoconus
Conditions
Interventions
Intervention 1: Intervention name: 5 min-UV radiation in corneal cross-linking
Intervention description: After local anesthesia with Proparacaine hydrochloride 0.5% eye drop, 3 or 4 vertical strips ab
Treatment - Surgery
Intervention name: 5 min-UV radiation in corneal cross-linking
Intervention description: After local anesthesia with Proparacaine hydrochloride 0.5% eye drop, 3 or 4 vertical strips about 2 mm wide r
The control intervention: 30 min-UV radiation in corneal cross-linking (routin treatment)
Control intervention description: After local anesthesia with Proparacaine hydrochloride 0.5% eye drop, 3 or
Sponsors
Noor eye hospital
Eligibility
Sex/Gender
All
Age
15 Years to 35 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: keratometry less than 60 diopter; central corneal thickness of 400 microns or more; keratoconus progression in the past 12 months documented as at least one D increase in maximum keratometry, or manifest cylinder; Bilateral surgery Exclusion criteria: diabetes and other systematic disease; use of corticosteroid and immunosupressive drugs in the past 6 months
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Corneal biomechanical assay. Timepoint: pre op, 1m, 3m and 6m after surgery. Method of measurement: Cornea status is evaluated by Ocular Response Analyzer (ORA), confoscan, and endothelial cell count (ECC). | — |
Secondary
| Measure | Time frame |
|---|---|
| Refraction. Timepoint: pre op, 1m, 3m and 6m after surgery. Method of measurement: autorefractometer.;Keratometry. Timepoint: pre op, 1m, 3m and 6m after surgery. Method of measurement: Pentacam.;Visual acuity. Timepoint: pre op, 1m, 3m and 6m after surgery. Method of measurement: Snellen chart. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSoheila Asgari
Noor eye hospital
Outcome results
None listed