post tympanoplasty nausea and vomiting. Other surgical procedures
Conditions
Interventions
Intervention 1: dexamethasone 8 mg IV immediately after intubation for all patients plus
granisetron 0.1 mg 15 minutes before extubation in group A. Intervention 2: granisetron 0.3 mg 15 minutes befo
Treatment - Drugs
dexamethasone 8 mg IV immediately after intubation for all patients plus
granisetron 0.1 mg 15 minutes before extubation in group A
granisetron 0.3 mg 15 minutes before extubation plus post intubation dexamethasone in group B
Ondansetron 4mg 15 minutes before extubation in addition to post intubation dexamethasone in group C
Sponsors
Research VICE chancellor of Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients that are candidate for tympanoplasty with ASA class I or II and age 15-60 year. Exclusion criteria: gastrointestinal diseases, history of treatment with anti emetics or drugs with anti emesis effects at 24 hours before surgery, BMI more than 36.5, pregnant or lactating mothers, opiate abuse, sensitivity reaction to studied drugs.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post operative nausea and vomiting. Timepoint: every 0-2 hours till 24 hours. Method of measurement: clinical monitoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Need for anti emetic drugs. Timepoint: every 0-2 hours till 24 hours. Method of measurement: Bellville score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Perovifar
Tabriz University of Medical Sciences
Outcome results
None listed