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Effect of mouthwash on tracheal colonization and pneumonia

Comparison of effect of three mouthwashs, chlorhexidin, sodium bicarbonate and salin on bacterial colonization of endotracheal tubes and incidence of pneumonia in patients undergoing open heart surgery in Imam Ali Hospitat 2012-2013.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201207204736N3
Enrollment
165
Registered
2012-07-26
Start date
2012-08-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pneumonia. Other pneumonia, organism unspecified

Interventions

Intervention 1: For the first group, two times a day and for 7 days after surgery, chlorhexidin 0.2% solution is used. Intervention 2: For the second group, two times a day and for 7 days after surger
Prevention
For the first group, two times a day and for 7 days after surgery, chlorhexidin 0.2% solution is used.
For the second group, two times a day and for 7 days after surgery, solution of sodium bicarbonate is used.
For the third group, two times a day and for 7 days after surgery, normal saline solution, is used.

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria consist of: lack of history of recent intubation; no history of recent surgery; no sensitivity to mouthwash solutions; having endotracheal tube; no symptoms of aspiration; the absence of debilitating disease of immune system; lack of use immunosuppressive drugs; age between 18-65 years and lack of periodontal disease. Exclusion criteria consist of: the patient died during surgery or the day after surgery; tracheal tube out before 6 hours after surgery; view aspiration revealed and incidence of allergic and unwanted reactions to chlorhexidin.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The amount of bacterial colonization of endotracheal tube. Timepoint: When extubation of tracheal tube. Method of measurement: Doing culture from endotracheal tube cuff in a laboratory.;Incidence of pneumonia. Timepoint: From entering to ICU and up to 7 days after admitted to surgical ward. Method of measurement: Chest radiography, measurement of body temperature, A complete blood count.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Khatony

Kermanshah School of Nursing and Midwifery

akhatony@kums.ac.ir+98 83 1827 9394

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026