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Study of serum prolactin level in women with Hyperthyroidism

Clinical trial on the effect of hyperthyroidism treatment on serum prolactine level in female hyperthyroidism patients of pregnancy age (15-50 y)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201207191774N4
Enrollment
160
Registered
2012-12-30
Start date
2012-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperthyroidism. Hyperthyroidism NOS

Interventions

Intervention 1: methimazole (20mg) is administered to the patients for 2 months. Intervention 2: in this study, primary serum level of prolactine before the initiation of metimazole administration is
Treatment - Drugs
methimazole (20mg) is administered to the patients for 2 months.
in this study, primary serum level of prolactine before the initiation of metimazole administration is considered as the control value. no drug/placebo group is defined for this study.

Sponsors

Vice chancellor for Research and Technology of kerman University of Medical Sciences, Physiology res
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Women with hyperthyroidism; Age between 15 to 50 years Exclusion criteria : use of drugs which increase prolactine level: dopamine receptor blocker including phenotiazine,chlorpromazin,perfenazine,butirofenon,haloperidole,thioxantine,metocloperamide ; dopamin synthesis inhibitor(etc. methyldopa) ;cathecolamin releasing agent: reserpin; Opiates ;H2 blockers including cimetidin,ranitidin; Imipramin,Amitriptylin; serotonin intake inhibitor:Fluoxetin; Calcium channel blockers:Verapamil; hormones: Estrogens;Antiandrogens,TRH; Others:pregnancy,lactation,liver disease,chronic kidney disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum prolactine level. Timepoint: Pre-treatment; post-treatment. Method of measurement: ICMA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mojgan Sanjari

Kerman afzalipour hospital

msanjari@kmu.ac.ir+98 341322225070

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026