Infertility. Complication associated with artificial fertilization, unspecified
Conditions
Interventions
Intervention 1: In intervention group (45 patients),at the same time of menses will applied 17-B estradiol transdermal patches 100 mcg every other day that each patch will removed after four days
Treatment - Drugs
In intervention group (45 patients),at the same time of menses will applied 17-B estradiol transdermal patches 100 mcg every other day that each patch will removed after four days .In both group c
In control group (45 patients), for endometrial preparation will started from 2nd day of cycle oral estradiol 6 mg daily. In both group clinical monitoring by transvaginal ultrasound will done on 1
Sponsors
Wise Canceler of Shahid Sadoughi University of Medical Sciences of Yazd,Research and Clinical Cente
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: female Exclusion criteria: FSH in day 3 of cycle more than 12 ; age below 20 and more than 40 years; bad qaulity vitrified/warmed embryo; polycystic ovarian syndrome ; endocrine or metabolic disorder;endometriosis ; egg donation
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial thickness. Timepoint: 10-20 days. Method of measurement: Measurement between two layers of endometrium by vaginal sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical pregnancy. Timepoint: 4-5 weeks after embryo transfer. Method of measurement: Observation of fetal heart activity by transvaginal sonography.;Time of endometrial preparation. Timepoint: 11-14 days. Method of measurement: Repeated vaginal sonography.;Cancelation rate of cycles. Timepoint: 10-20 days. Method of measurement: Repeated vaginal sonography.;Chemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: BHCG test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Sima Janati
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences Yazd
Outcome results
None listed