Hemodynamic Change. Postprocedural disorder of circulatory system, unspecified
Conditions
Interventions
Intervention 1: Control group: Normal saline + 0.2 mg/kg Etomidate. Intervention 2: Intervention group: 1 mg/kg Ketamine + 1.5 mg/kg Propofol.
Treatment - Drugs
Control group: Normal saline + 0.2 mg/kg Etomidate
Intervention group: 1 mg/kg Ketamine + 1.5 mg/kg Propofol
Sponsors
Vice chancellor for research of Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: First time elective CABG surgery; Age between 40 and 70 years; EFMAP>110 mmHg; CABG with valve operation; Received etomidate or propofol or thiopental in one week ago; Egg and soy allergy; Sensitivity to etomidate or propofol or ketamine; Adrenal insufficiency
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure. Timepoint: Before laryngoscopy as well as immediately, 1, 2 and 3 min after tracheal intubation. Method of measurement: Invasive Blood Pressure.;Systolic blood pressure. Timepoint: Before laryngoscopy as well as immediately, 1, 2 and 3 min after tracheal intubation. Method of measurement: Invasive Blood Pressure.;Diastolic blood pressure. Timepoint: Before laryngoscopy as well as immediately, 1, 2 and 3 min after tracheal intubation. Method of measurement: Invasive Blood Pressure.;Heart rate. Timepoint: Before laryngoscopy as well as immediately, 1, 2 and 3 min after tracheal intubation. Method of measurement: Heart monitoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Muscle twitching. Timepoint: After anesthetic infusion. Method of measurement: Inspection.;Pain on injection. Timepoint: After anesthetic infusion. Method of measurement: Inspection. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAfshin Gholipour Baradari, MD
Mazandaran University Of Medical Sciences
Outcome results
None listed