Magnesium sulfate prescription for patients with severe preeclampsia

A comparison between 2 methods of magnesium sulfate administration for 12 or 24 hours after delivery in patients with severe preeclampsia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201207182624N10

Enrollment

Registered

2013-04-23

Start date

2012-07-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preeclampsia. Pregnancy, childbirth and the puerperium, Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

Interventions

Intervention 1: Magnezium sulphate ( formula,Magnezium sulphate , 7 H2o) prescription Magnesum sulfate ( 10 gram intramuscular+ 4 gram intravenous= 14 gram) stat and then 5 gram every 4 hours for 1

Magnesum sulfate ( 10 gram intramuscular+ 4 gram intravenous= 14 gram) stat and then 5 gram every 4 hours for 24 houres after delivery.

Treatment - Drugs

Magnezium sulphate ( formula,Magnezium sulphate , 7 H2o) prescription Magnesum sulfate ( 10 gram intramuscular+ 4 gram intravenous= 14 gram) stat and then 5 gram every 4 hours for 12 hours after de

Magnezium sulphate ( formula,Magnezium sulphate , 7 H2o) prescription

Magnesum sulfate ( 10 gram intramuscular+ 4 gram intravenous= 14 gram) stat and then 5 gram every 4 hours for 24 houres after delivery

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: severe preeclampsia: one or more options from what comes below: systolic blood pressure of 160 mmHg or more; diastolic blood pressure of 110 mmHg or more; proteinuria 2+ and more; persistent headache or visual disturbances or persistent epigastric pain convulsion; increased creatininemore than 1.2 mg per dl without previous rise; platelet count less than 100000 per micro liter; pulmonary edema.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Convulsion. Timepoint: any timd during 12 and 24 hours. Method of measurement: convulsion according to documents and observation.	—

Secondary

Measure	Time frame
Maternal mortality and morbidity, cerebral hemorrhage. Timepoint: Any time during 24 houres after delivery. Method of measurement: Maternal mortality and cerebral hemorrhage according to documents and observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Kashanian

Iran University of Medical Sciences

maryamkashanian@yahoo.com+98 21 5563 3244

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026