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The effect of probiotic supplementation on sexual performance

The effect of probiotic supplementation on sexual function in perimenopausal and menopausal women: A randomized controlled clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120718010324N83
Enrollment
64
Registered
2024-05-11
Start date
2024-05-19
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexual dysfunction. F52

Interventions

Intervention 1: Intervention group: Participants (32 people) will take one 250 mg probiotic capsule daily at lunch, before or between meals with a full glass of water for eight weeks. Intervention 2:

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Married women aged 40 to 60 years with menstrual irregularity or menopause Having sex at least twice a month Her husband being monogamous Women's sexual function index questionnaire score FSFI<28 in the initial assessment ? A minimum of 12 months and a maximum of 10 years have passed since menopause in menopausal people ? Occurrence of natural menopause in menopausal people and not following hysterectomy surgery or GnRH receptor agonist drugs

Exclusion criteria

Exclusion criteria: Allergy to any of the products containing probiotics Use of any immunosuppressive drugs Use of drugs that affect sexual performance by the person himself or his wife History of hormonal treatment due to sexual dysfunction during the last two weeks Bleeding or spotting after intercourse, vaginal infection Women who use sexual performance enhancing drugs Addiction of spouses to drugs or alcohol The presence of chronic diseases such as heart disease, diabetes, lupus, mental disorders, etc. History of complete hysterectomy Anatomical deformity of the external genitalia History of pelvic chemotherapy and radiotherapy Severe emotional stress during the 3 months before the start of the study Use of phytoestrogens and other herbal medicines Urinary incontinence

Design outcomes

Primary

MeasureTime frame
Average sexual performance score. Timepoint: At the beginning of the study and eight weeks after the start of the intervention. Method of measurement: Female Sexual Function Index (FSFI) questionnaire.

Secondary

MeasureTime frame
Average quality of life score. Timepoint: At the beginning of the study and eight weeks after the start of the study. Method of measurement: Menopause-Specific Quality of Life questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoghayyeh Valizadeh

Tabriz University of Medical Sciences

r.valizadeh31@gmail.com+98 41 3523 0741

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026