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Effect of Probiotic Supplementation on the Incidence of Urinary Tract Infection in the Postpartum Period

The Effect of Lactobacillus Acidophilus Probiotic Supplementation on the Incidence of Urinary Tract Infection in the Postpartum Period: A Randomized Controlled Clinical Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120718010324N81
Enrollment
234
Registered
2024-01-04
Start date
2023-12-31
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary tract infection. Urinary tract infection following delivery

Interventions

Intervention 1: Intervention group: The intervention group will take a 500 mg probiotic capsule of Lactobacillus acidophilus strain daily with a glass of water at lunch for 8 weeks. Lactobacillus acid

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
10 Years to 54 Years

Inclusion criteria

Inclusion criteria: Childbirth experience in the last 48 hours Negative urine culture at the time of entering the study

Exclusion criteria

Exclusion criteria: Regular consumption of fermented dairy products containing probiotics, especially yogurt, cheese, and buttermilk 2 weeks before the start of the study Allergy to any of the products containing probiotics Conditions that require additional antibiotics during the puerperal period Use of any immunosuppressive drugs Having high-risk disease conditions

Design outcomes

Primary

MeasureTime frame
The incidence of urinary tract infection (cystitis, pyelonephritis, asymptomatic bacteriuria). Timepoint: During the study and two months after the start of the intervention. Method of measurement: Urine culture and checklist of urinary infection symptoms.

Secondary

MeasureTime frame
Breastfeeding performance. Timepoint: Two months after the start of the intervention. Method of measurement: Breastfeeding performance questionnaire.;Quality of life. Timepoint: Two months after the start of the intervention. Method of measurement: Quality of life questionnaire.;Appropriate weight gain for the baby. Timepoint: Two months after the start of the intervention. Method of measurement: Scale.;The level of satisfaction with the received intervention. Timepoint: Two months after the start of the intervention. Method of measurement: Satisfaction checklist.;Side events. Timepoint: During the study. Method of measurement: Checklist of side events.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Borhani Soureh

Tabriz University of Medical Sciences

mid.fatemeborhani@gmail.com+98 41 3523 0741

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026