Vaginal Candidiasis. Candidiasis of vulva and vagina
Conditions
Interventions
Intervention 1: Intervention group 1 will use Mycozin vaginal cream at bedtime for one week. Intervention 2: Intervention group 2 will use Clotrimazole 1% vaginal cream at bedtime for one week.
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Age 18-45 years married Being literate in reading and writing Lack of allergy to herbal medicines Suffering from candidal vaginitis
Exclusion criteria
Exclusion criteria: Suffering from chronic diseases such as diabetes, AIDS, immune system disorders, depression, etc. currently, according to the participant's statement Taking antibiotics and corticosteroids during the last two weeks according to the participant's statement Menstruation at the time of study Current use of oral contraceptives as reported by the participant The presence of a wound or mass in the cervix when viewed with a speculum Existence of severe mental stress during the last three months, such as the death of first-degree relatives Presence of pregnancy or breastfeeding at the time of study Taking other drugs to treat vaginitis Having recurrent vulvovaginitis (more than four times per year) Abnormal uterine bleeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of clinical symptoms (smell, quantity, consistency, color and appearance of vaginal secretions, vaginal inflammation, appearance of cervix). Timepoint: Before the intervention and 10 to 15 days after the intervention. Method of measurement: Clinical examination by the researcher and clinical symptoms checklist.;Frequency of patient complaints (secretions, dysuria, frequency, itching, itching during intercourse, pain in the lower abdomen, burning sensation during intercourse, and dyspareunia). Timepoint: Before the intervention and 10 to 15 days after the intervention. Method of measurement: Stated by the participants and complaints checklist.;Frequency of laboratory symptoms (negative smear and culture of vaginal secretions). Timepoint: Before the intervention and 10 to 15 days after the intervention. Method of measurement: Sampling will be done with a sterile cotton swab from the posterior fornix of the vagina, and we will dip the swab inside the blood culture tubes and gently shake it inside the solution until the sample dissolves in it. Incubation will be at 37 degrees for 2 to 4 hours, and a drop of the contents of the tube solution will be transferred on a slide. We examine the slide under the microscope with high and low magnification. Germ tube formation test is a quick test to identify Candida albicans and differentiate it from other yeasts. | — |
Secondary
| Measure | Time frame |
|---|---|
| PH of vaginal secretions. Timepoint: Before the intervention and 10 to 15 days after the intervention. Method of measurement: PH paper.;Satisfaction with the treatment. Timepoint: 10 to 15 days after the intervention. Method of measurement: Satisfaction questionnaire.;Side events. Timepoint: 10 to 15 days after the intervention. Method of measurement: Side events checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Khadijeh Hajizadeh
Tabriz University of Medical Sciences
Outcome results
None listed