Condition 1: Depression. Condition 2: Sleep quality. Depressive episode Sleep disorder, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Each person will receive 90 magnesium tablets of 250 mg made by Galenus company for 12 weeks. One tablet will be taken daily with a glass of water. Intervention 2
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: Women who are 45 to 60 years old. At least one year has passed since their last period. Mild and moderate depression based on the Beck questionnaire (score 14 to 28) Diagnosis of inappropriate sleep quality based on the Pittsburgh questionnaire (scores 6 to 21)
Exclusion criteria
Exclusion criteria: Having other psychotic disorders such as schizophrenia and active delusions ,Insanity, Bipolar disease, Dementia according to the person's self-report or medical record Regular use of supplements and minerals, especially magnesium, in the last few months Having diseases such as kidney disease (the active role of the kidney in magnesium homeostasis) and myasthenia gravis (due to the aggravation of the disease by magnesium) and gastrointestinal disease (diarrhea is a common side effect of magnesium) according to the individual's statement or the medical record. Planned surgery within the next three months (due to the incomplete continuation of the treatment process) Using drugs that interfere with magnesium (drugs such as Eltrombopag, Baloxavir, Tetracycline, Marboxil, Demeclocycline, Doxycycline, Minocycline, Oxytetracycline) The existence of recent crises in life
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression. Timepoint: Before the start of the intervention, one month after the start of the intervention, after the end of the intervention. Method of measurement: Beck depression questionnaire.;Sleep quality and its subdomains. Timepoint: Before the start of the intervention, one month after the start of the intervention, after the end of the intervention. Method of measurement: Pittsburgh Sleep Quality Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life and its subdomains. Timepoint: Before the start of the intervention, after the end of the intervention. Method of measurement: Menopause Quality of Life (MENQOL) questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Alizadeh
Tabriz University of Medical Sciences
Outcome results
None listed