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The effect of curcumin on the premenstrual syndrome and dysmenorrhea

The effect of oral capsule of curcumin on the premenstrual syndrome and dysmenorrhea among students in Tabriz, Iran: a randomized controlled trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120718010324N71
Enrollment
62
Registered
2022-09-18
Start date
2022-09-20
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Premenstrual syndrome. Condition 2: Dysmenorrhea. Premenstrual tension syndrome Primary dysmenorrhea

Interventions

Intervention 1: Intervention group: The participants (31 people) will receive curcumin oral supplement in the form of gelatin capsules with a dosage of 500 mg with the trade name (Curcuma longa extrac
NOW®). Curcumin supplement contains a combination of curcumin and phosphatidylcholine. The time to take the supplement is once a day and after a meal. The duration of taking the supplement will be 10

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Regular menstruation (21-35 days) Having primary dysmenorrhea and premenstrual syndrome (with VAS score = 4 and PSST score = 20) Age 18-25 years Not allergic to turmeric Not taking any medicine to treat the symptoms of premenstrual syndrome at the same time as the research

Exclusion criteria

Exclusion criteria: Abuse of tobacco and alcohol Use of other herbal medicines The occurrence of a stressful event (such as the death of a first-degree family member and the diagnosis of an incurable disease for a family member during the last three months) Having any acute or chronic disease (such as epilepsy, cardiovascular, digestive, liver, blood, endocrine) History of any gynecological disease, such as abnormal pelvic anatomy, lack of ovulation, or abnormal pattern of uterine bleeding. Surgery in the last three months Taking antidepressants (such as serotonin and noradrenaline reuptake inhibitors, antihistamines, barbiturates, narcotics, diazepam, amphetamines, and cocaine) Taking anticoagulants such as heparin, aspirin, clopidogrel, dipyridamole, warfarin, enoxaparin and ticlopidine.

Design outcomes

Primary

MeasureTime frame
Premenstrual syndrome. Timepoint: The first assessment before entering the study and the second assessment in one month after the intervention and the third assessment in 2 months after the intervention. Method of measurement: Premenstrual symptoms screening tool (PSST).;Dysmenorrhea. Timepoint: The first assessment before entering the study and the second assessment in one month after the intervention and the third assessment in 2 months after the intervention. Method of measurement: Visual analogue scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSepideh Mashayekh Amiri

Tabriz University of Medical Sciences

Sepidehmashayekh@yahoo.com+98 41 3479 6770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026