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The effect of curcumin on painful symptoms of endometriosis

The effect of curcumin on painful symptoms of endometriosis: a randomized controlled trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120718010324N66
Enrollment
68
Registered
2021-03-01
Start date
2021-03-19
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis. Endometriosis

Interventions

Intervention 1: Intervention group: The intervention group will receive curcumin capsules at a dose of 500 mg twice a day for eight weeks. Curcumin and placebo capsules will be prepared by Dineh Pharm

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Women with endometriosis whose endometriosis has been confirmed by laparoscopy Women with symptomatic endometriosis Not taking of anti-inflammatory or hormonal medication in the last three months Not having endometrial hypoplasia or neoplasia Women who are married and sexually active

Exclusion criteria

Exclusion criteria: Women who have allergic to ginger plants Women with gallstones, jaundice due to bile duct obstruction, and acute biliary colic Women with gastrointestinal diseases

Design outcomes

Primary

MeasureTime frame
Painful symptoms of endometriosis. Timepoint: Before the intervention and 8 weeks after starting of intervention. Method of measurement: ENDOPAIN-4D questionnaire.

Secondary

MeasureTime frame
Quality of life. Timepoint: Before the intervention and 8 weeks after starting the intervention. Method of measurement: EHP-30 questionnaire.;Severity of dysmenorrhea. Timepoint: The first three days of the menstrual cycle before the intervention and then the first three days of the next two cycles. Method of measurement: VAS ruler.;Frequency of analgesic use. Timepoint: During the intervention. Method of measurement: Checklist.;Side effects. Timepoint: During the intervention. Method of measurement: Side effects checklist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhaneh Goodarzi

Tabriz University of Medical Sciences

reyhan26673@gmail.com+98 41 3177 2048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026