polycystic ovary syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: The intervention group receives two oral capsules of curcumin at a dose of 500 mg for 12 weeks. Intervention 2: The control group received two oral capsules daily from 500 mg for 12 we
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Willingness to participate in the study Having sufficient literacy to complete the questionnaire or the presence of a literate person in the family Having polycystic ovarian syndrome BMI Between 25 and 40
Exclusion criteria
Exclusion criteria: Having other androgenic disorders, such as adrenal hyperplasia or a androgen secreting tumors Having thyroid gland diseases having Cushing's syndrome Taking hormonal contraceptives currently or using hormonal therapy Pregnancy or breastfeeding Previous surgery on one or both ovaries Smoking and drinking alcohol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum levels of metabolic factors (fasting insulin, fasting blood glucose, LDL, HDL, and cholesterol). Timepoint: Before and 12 weeks after intervention with drug/placebo. Method of measurement: Blood test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hirsutism Score. Timepoint: Before and 12 weeks after intervention with drug/placebo. Method of measurement: Ferriman–Gallwey criteria.;Anthropometric indices (waist circumference, hip circumference and body mass index). Timepoint: Before and 12 weeks after intervention with drug/placebo. Method of measurement: Measuring with centimeter and scale.;Menstrual status. Timepoint: Before and 12 weeks after intervention with drug/placebo. Method of measurement: Menstrual characteristics questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNilufar Ggahnbarzade Gashti
Tabriz University of Medical Sciences
Outcome results
None listed