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The effect of curcumin and vitamin E on hot flush and anxiety in postmenopausal women

The effect of oral capsule of curcumin and vitamin E on the hot flush and anxiety in postmenopausal women: a triple blind randomised controlled trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120718010324N44
Enrollment
93
Registered
2018-06-23
Start date
2018-07-04
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: hot flush. Condition 2: anxiety. Menopausal and female climacteric states Anxiety disorder, unspecified

Interventions

Intervention 1: The first Intervention group will receive oral capsules of curcumin twice a day at a dose of 500 milligrams for eight weeks. Intervention 2: The second intervention group will receive

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Willingness to participate in the study Having sufficient literacy to complete the questionnaire or the presence of a literate person in the family Normal menopause Being married Women who have been under 6 years old since their menopause. Having at least 40 years and a maximum of 60 Having hot flush at least twice a week

Exclusion criteria

Exclusion criteria: Use of tobacco and alcoholic beverages and herbal medicines Stressful factors such as the death of relatives in the first six months of the past and loss of occupation Known psychiatric or systemic problems including cardiovascular, digestive, liver, endocrine, etc. Use of any effective medicines for hot flashes (Clonidine, Methyl dopa, Gabapentin, Selective Serotonin Reuptake Inhibitors (SSRIs), Norepinephrine inhibitors (SNRI), and Soy isoflavone Factors that cause vasomotor disorder, such as thyroid disease, according to the person expression Use of any effective medication to treat a person's sexual response (Antihypertensive, Thiazide diuretics, Antidepressant drugs such as Serotonin and Noradrenaline and Reuptake, Antihistamines, Barbiturates, Narcotics, Diazepam, Amphetamines, Cocaine History of allergy to turmeric or other drugs, food and color Taking anticoagulant drugs (Hyarin, Warfarin, Enoxaparin)

Design outcomes

Primary

MeasureTime frame
Hot flush. Timepoint: Before the intervention, 4 and 8 weeks after the intervention. Method of measurement: Hot flush checklist.;Anxiety. Timepoint: Before the intervention, 4 and 8 weeks after the intervention. Method of measurement: State- Trait Anxiety Inventory.

Secondary

MeasureTime frame
Sexual function. Timepoint: Before the intervention, 4 and 8 weeks after the intervention. Method of measurement: FSFI= Female Sexual Function Inventory.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhatereh Ataei

Tabriz University of Medical Sciences

khaterehatayi@gmail.com+98 41 4438 8341

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026