The role of propranolol with L-carnitine in the prophylactic treatment of cyclic vomiting syndrome

Comparison of the effect of propranolol alone and propranolol with L-carnitine in the prophylactic treatment of cyclic vomiting syndrome in children

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120716010297N9

Enrollment

104

Registered

2020-08-17

Start date

2020-08-22

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cyclic vomiting syndrome. Cyclical vomiting

Interventions

Intervention 1: Intervention group 1: Patients receive propranolol tablets (Poursina Pharmaceutical Co.) at a dose of 1 mg/kg daily with L-carnitine tablets (Poursina Pharmaceutical Co.) at a dose of

Eligibility

Sex/Gender

All

Age

3 Years to 18 Years

Inclusion criteria

Inclusion criteria: cyclic vomiting syndrome with more than two attacks in a month No seizures No metabolic diseases No gastrointestinal diseases

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Incidence of vomiting attacks. Timepoint: Before and during 6 months after the start of the intervention. Method of measurement: Observation.;Severity of vomiting attacks. Timepoint: Before and during 6 months after the start of the intervention. Method of measurement: Visual scale(Score 1 lowest severity and score 10 highest severity of vomiting attacks).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Famouri

Esfahan University of Medical Sciences

fat.famoori@gmail.com+98 31 3668 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026