adult active Rheumatoid arthritis. Rheumatoid arthritis, unspecified
Conditions
Interventions
Intervention 1: Intervention Group: Patients that refer to hospital shariatti have interval criteria and will receive Ginger voluntarily. Patients in case group will receive 1500 mg of powdered Ginge
Treatment - Other
Placebo
Intervention Group: Patients that refer to hospital shariatti have interval criteria and will receive Ginger voluntarily. Patients in case group will receive 1500 mg of powdered Ginger daily (by two
Control groups: Patients that refer to hospital shariatti have interval criteria and will receive starch or flour voluntarily. Patients in Control group will receive 1500 mg of wheat flour daily (by
Sponsors
Vice-chancellor for Research, Tehran University of Medical Sciences, Vice chancellor for Research, I
Eligibility
Sex/Gender
All
Age
18 Years to 69 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: person with RA diseases as ACR criteria, having RA from 2 years ago; age between 18-69 years; not being pregnant or lactated; not smoking and drink alcohol; haven’t eaten multivitamin or antioxidants supplements from 3 month ago; don't eat lowering blood pressure; don't eat anti pregnancy drugs, exclusion criteria: Changes in diet or physical activity every day; taking less than 80% of supplements given to patients at baseline(the compliance lower than %80); consumption of contraceptives, multivitamins and antioxidant supplements; renal , hepatic , thyroid, parathyroid diseases, cancer, heart diseases
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| BMI. Timepoint: Before and after intervention. Method of measurement: weight(kg)/height(m*2).;Nsaids intake. Timepoint: Before and after intervention. Method of measurement: questionnaire. | — |
Primary
| Measure | Time frame |
|---|---|
| HsCRP. Timepoint: Before and after intervention. Method of measurement: Elisa.;IL17. Timepoint: Before and after intervention. Method of measurement: ELISA.;TNFa. Timepoint: Before and after intervention. Method of measurement: ELISA.;IL10. Timepoint: Before and after treatment. Method of measurement: ELISA.;IL2. Timepoint: Before and after intervention. Method of measurement: ELISA.;DAS28. Timepoint: Before and after study. Method of measurement: using ESR,CRP and number of joints with inflammation.;IL4. Timepoint: Before and after treatment. Method of measurement: ELISA.;ESR. Timepoint: Before and after the study. Method of measurement: Westergern method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNaheed Aryaeian
Nutrition faculty, Iran University of Medical Sciences
Outcome results
None listed