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The effect of premedication on'' anxiety'','' pain'' and'' vital signs'' of patients with coronary angiography

The effect of premedication on'' anxiety'','' pain'' and'' hemodynamic status'' of patients undergoing coronary angiography Ganjaviyan Hospital Dezful in 1390: a blind randomized clinical trial interpretations

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012071010235N1
Enrollment
102
Registered
2012-12-31
Start date
2012-05-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac catheterization. Angina pectoris

Interventions

Intervention 1: In group A the hemodynamic status and anxiety level were recorded 8 to 12 hours and half an hour prior to coronary angiography, then they recieved 4mg IV Chlorpheniramine and 100mg IV
Treatment - Drugs
Placebo
In group A the hemodynamic status and anxiety level were recorded 8 to 12 hours and half an hour prior to coronary angiography, then they recieved 4mg IV Chlorpheniramine and 100mg IV Hydrocortizon,
In group B the hemodynamic status and anxiety level were recorded 8 to 12 hours and half an hour prior to coronary angiography, then they recieved 5mg IV Diazepam and 100mg IV Hydrocortizon, 0/5 to 1
In group C the hemodynamic status and anxiety level were recorded 8 to 12 hours and half an hour prior to coronary angiography, then they recieved 2mg IV Normalsalin and 100mg IV Hydrocortizon, 0/5 to

Sponsors

Research Vice-Chancellor of Ahvaz Jundishapur University of Medical Sciences
Lead Sponsor
Arvand International Division, Ahvaz Jundishapur University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Having coronary angiography for the first time ; Patients aged 30-70 years ; Having just coronary angiography without right heart catheterization ; Having no history of invasive procedures before angiography such as Trans'' Esophageal Echocardiogram''. Exclusion criteria: History of recent myocardial infarction( during last week); History of severe heart failure, Heart valves disease or congenital heart disease; Hemodynamic'' istability'' ; History of severe anxiety.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Anxiaty severity. Timepoint: 8-12 hours and half an hour before coronary angiography and during coronary angiography. Method of measurement: Whether having anxiety by asking a question and anxiety level by VAS criteria.;Pain severity. Timepoint: During Angiography and after in time of arrival and 2,4,6 hours after coronary angiography. Method of measurement: Whether Having pain by asking a question and pain level by VAS criteria.;Hemodynamic status. Timepoint: 8-12 hours and half an hour before coronary angiography and every 5 minutes during procedure then every 15 minutes after procedure. Method of measurement: By Control pulse, respiration, temperature, systolic and diastolic blood pressure.

Secondary

MeasureTime frame
Measure rate sensitivity to pain. Timepoint: One hour before injection of the premedication. Method of measurement: The heels with a needle at a distance 5 cm.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFakharzadeh Leyla

Medical and Health Services, Ahwaz Jondi Shapur - The International Arvand

Fakharzadehl@yahoo.com00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026