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Effect of Midazolam on perception and consciousness during surgery

Effect of Midazolam on perception and consciousness during surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201207086480N3
Enrollment
154
Registered
2012-08-10
Start date
2012-07-13
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative awareness. Other symptoms and signs involving cognitive functions and awareness

Interventions

Intervention 1: The intervention group receive 2.5 mg intravenous Midazolam 15 minutes before induction of anesthesia. After the pre-oxygenation they are placed under anesthesia with the 5 mg / kg of
In the control group after pre-oxygenation they are placed under anesthesia induction with the 5 mg / kg of thiopental and 1.5 mg/ kg of Succinylcholine, continuation of anesthesia is done using Halot
The intervention group receive 2.5 mg intravenous Midazolam 15 minutes before induction of anesthesia. After the pre-oxygenation they are placed under anesthesia with the 5 mg / kg of Thiopental and 1

Sponsors

vice chancellory for research, Shahrekord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patients who are candidate for elective surgery class A, Two ASA classification, 1 hour for operation length, the age ranges between 15-45 years old. Exclusion criteria: having every kind of hearing problems, neurological disease, addiction, using drugs affective for Psychiatry and patients who are referred to ICU after operation because of specific condition.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Increasing depth of anesthesia. Timepoint: Intraoperation. Method of measurement: Questionnaire.;Recalling the memories. Timepoint: 1 hour after operation. Method of measurement: Questionnaire.

Secondary

MeasureTime frame
Tearing. Timepoint: Intraoperation. Method of measurement: Questionnaire.;Tachycardia. Timepoint: Intraoperation. Method of measurement: Questionnaire.;Dream in action. Timepoint: 1 hour after operation. Method of measurement: Questionnaire.;Hearing the conversation intraoperation. Timepoint: 1 hour after operation. Method of measurement: Questionnaire.;Pain. Timepoint: 1 hour after operation. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ebrahim Pouria Monfared

Ayatollah Kashani hospital

forouzanganji@skums.ac.ir+98 38 1226 4825

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026