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The role of stem cells in hypertrophic scar improvement

Clinical trial of assessing the effect of using adipose-derived stem cells in improving trauma, surgical and burn induced hypertrophic scars

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012070710201N1
Enrollment
60
Registered
2012-10-04
Start date
2012-10-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophic Scar. Hypertrophic scar

Interventions

Intervention 1: 0.5 cc N/S injection per 1 square Cm of controls scar. Intervention 2: 0.5 cc fat derived stem cell injection per 1 square cm of cases scar.
Placebo
Treatment - Drugs
0.5 cc N/S injection per 1 square Cm of controls scar
0.5 cc fat derived stem cell injection per 1 square cm of cases scar

Sponsors

Tehran University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with hypertrophic scar. Exclusion criteria: Patient's reluctance to continue cooperation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Vascularity. Timepoint: 3, 6 months and 1 year. Method of measurement: Inspection.;Pigmentation. Timepoint: 3 , 6 months and 1 year. Method of measurement: Inspection.;Pliability. Timepoint: 3 , 6 months and 1 year. Method of measurement: palpation.;Height. Timepoint: 3 , 6 months and 1 year. Method of measurement: Measurement with caliper.;Vancouver Scoring System. Timepoint: 3 , 6 months and 1 year. Method of measurement: Inspection and Palpation.

Secondary

MeasureTime frame
Scar Tissue Increment. Timepoint: 3 , 6 months and 1 year. Method of measurement: Inspection and measurment with caliper.;Pruritus. Timepoint: 3 , 6 months and 1 year. Method of measurement: Patient Expression.;Burning. Timepoint: 3 , 6 months and 1 year. Method of measurement: Patient Expression.;Injection Site Infection and Inflammation. Timepoint: Up to 1 month. Method of measurement: Diagnosis by physician.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbolfazl Abbaszadeh

Tehran University Of Medical Sciences

a-abbaszadeh@razi.tums.ac.ir+98 21 8871 0099

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026