The effectiveness of sesame oil in breast radiotherapy burns

Efficacy of sesame oil versus placebo in the management of acute radiation-induced dermatitis in breast cancer patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120707010205N9

Enrollment

Registered

2021-07-11

Start date

2021-07-03

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute radiation-induced dermatitis in breast cancer patients. Radiodermatitis, unspecified

Interventions

Intervention 1: Intervention group: Sesame oil: After each session of radiotherapy, patients should use 3 cc of sesame oil in the breast area that has undergone radiotherapy so that the solution is sp

Eligibility

Sex/Gender

Female

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: All patients should complete the adjuvant chemotherapy before starting bilateral breast radiotherapy. Non-metastatic female patients with breast cancer who underwent lumpectomy Patients should be 18 to 75 years old

Exclusion criteria

Exclusion criteria: Patients with collagen-vascular diseases Patients with a history of previous radiotherapy Having an active infection during the study Patients with allergies to sesame oil (or placebo)

Design outcomes

Primary

Measure	Time frame
Score of acute dermatitis according to the staging system of the Radiation Oncology Group (RTOG). Timepoint: At the beginning of the study (before the intervention) and 7, 14 and 21 and the last day after the start of sesame oil consumption. Method of measurement: RTOG criteria to evaluate acute skin reaction.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDariush Muslimi

Babol University of Medical Sciences

info@mubabol.ac.ir+98 11 3219 9592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026