Evaluation of the effects of quercetin ointment in the prevention of radiation-induced acute proctitis in prostate cancer patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120707010205N10

Enrollment

Registered

2022-09-19

Start date

2022-05-22

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radiation proctitis. Radiation proctitis

Interventions

Intervention 1: Intervention group: concurrent with beginning of radiotheray,every day 5 cc of prepared quercetin ointment will be used by enema twice

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: prostate cancer patients undergoing radiotherapy with a field encompassing almost whole rectum and receive a minimum dose of 4000 cGy radiation

Exclusion criteria

Exclusion criteria: Patients with history of previous radiotherapy of pelvis region Patients receiving treatment with anti-inflammatory drugs (NSAIDS, corticosteroids) Patients with inflammatory bowel disease (ulcerative colitis , Crohn's disease )

Design outcomes

Primary

Measure	Time frame
Score of acute proctitis according to the staging system of the Radiation Oncology Group (RTOG). Timepoint: At the beginning of the study and then every week after the start of quercetin ointment consumption. Method of measurement: RTOG criteria to evaluate acute proctitis reaction induced by radiation therapy.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Dariush Moslemi

Babol University of Medical Sciences

moslemi_d@yahoo.com+98 11 1223 4143

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026