Comparison the effects of uterotonic constrictors in caesarean section under spinal anesthesia

Comparison the effects of Oxytocin and Methylergonovine in elective caesarean section under spinal anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201207055751N3

Enrollment

Registered

2012-07-19

Start date

2012-06-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caesarean section. Delivery by caesarean section, unspecified

Interventions

Intervention 1: Intervention Name: Methylergonovine Intervention Description: After fetus delivery , 0.2mg Methylergonovine in 1 liter isotonic serum in case group will be infusion. Intervention 2: In

Treatment - Drugs

Intervention Name: Methylergonovine Intervention Description: After fetus delivery , 0.2mg Methylergonovine in 1 liter isotonic serum in case group will be infusion

In control group: Oxytocin 30 unit in one liter isotonic serum will be infused after fetus delivery

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria consist of: Elective caesarean section Exclusion criteria consist of: positive history of cardiovascular disease; positive history of preeclampsia; emergent caesarean section; factors increasing risk of uterine atony

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Systolic Blood Pressure. Timepoint: In minutes 1,3,5 after spinal anesthesia and in minutes 1,3,5,10,15,20 after drug administration. Method of measurement: Non Invasive Blood Pressure Monitoring.;Diastolic Blood Pressure. Timepoint: In minutes 1,3,5 after spinal anesthesia and in minutes 1,3,5,10,15,20 after drug administration. Method of measurement: NonInvasive Blood Pressure Monitoring.;Heart Rate. Timepoint: In minutes 1,3,5 after spinal anesthesia and in minutes 1,3,5,10,15,20 after drug administration. Method of measurement: Non Invasive Blood Pressure Monitoring.;Mean Arterial Blood Pressure. Timepoint: In minutes 1,3,5 after spinal anesthesia and in minutes 1,3,5,10,15,20 after drug administration. Method of measurement: Non Invasive Blood Pressure Monitoring.	—

Measure

Time frame

Systolic Blood Pressure. Timepoint: In minutes 1,3,5 after spinal anesthesia and in minutes 1,3,5,10,15,20 after drug administration. Method of measurement: Non Invasive Blood Pressure Monitoring.;Diastolic Blood Pressure. Timepoint: In minutes 1,3,5 after spinal anesthesia and in minutes 1,3,5,10,15,20 after drug administration. Method of measurement: NonInvasive Blood Pressure Monitoring.;Heart Rate. Timepoint: In minutes 1,3,5 after spinal anesthesia and in minutes 1,3,5,10,15,20 after drug administration. Method of measurement: Non Invasive Blood Pressure Monitoring.;Mean Arterial Blood Pressure. Timepoint: In minutes 1,3,5 after spinal anesthesia and in minutes 1,3,5,10,15,20 after drug administration. Method of measurement: Non Invasive Blood Pressure Monitoring.

—

Secondary

Measure	Time frame
?Amount of bleeding after drug administration. Timepoint: In operation room and recovery room. Method of measurement: Suctioned blood volume in bottle and field of surgery.;Time of uterine atony. Timepoint: After fetus delivery. Method of measurement: Taking the time of delivery of fetus up to uterine contraction.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbdolrasoul Anvaripour

Bushehr University of Medical Sciences

anvari@bpums.ac.ira.anvari.p@hotmail.com+98 77 1252 6802

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026