Comparison of Pregabalin and Sodium Valproate on prophylaxis of migraine type headache

Comparison of the efficacy of prophylaxis with Pregabalin and Sodium Valproate on intensity and frequency of migraine type headache in Iranian patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012070310178N1

Enrollment

100

Registered

2013-04-21

Start date

2013-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. Migraine

Interventions

Intervention 1: Control: Sodium Valproate 200 mg BID for 3 months. Intervention 2: Intervention: Pregabalin 75mg twice daily for 3 months.

Treatment - Drugs

Control: Sodium Valproate 200 mg BID for 3 months

Intervention: Pregabalin 75mg twice daily for 3 months

Eligibility

Sex/Gender

All

Age

15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:all patients with diagnosis of migraine based on International Headache Society criteria. Exclusion criteria: other types of headache; administration of prophylactic treatment for migraine; pregnancy; breast feeding; sensitivity to Pregabalin or Sodium Valproate.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Frequency of migraine type headaches. Timepoint: entrance to study, 1, 2 and 3 months after intervention. Method of measurement: history taking and patient's notes.;Intensity of migraine headaches. Timepoint: entrance to study, 1, 2 and 3 months after intervention. Method of measurement: Wong-Baker Faces Pain Rating Scale.	—

Secondary

Measure	Time frame
Consumption of analgesics. Timepoint: entrance to the study, 1, 2 and 3 months after intervention. Method of measurement: history taking and patient's notes.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Sistanizad

Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences

sistanizadm@sbmu.ac.ir+98 218800087

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026