Effect of high dose vitamin D in patients with ischemic stroke

Effect of high dose vitamin D on serum Neuron Specific Enolase (NSE) level as a marker of neuronal damage in patients with ischemic stroke

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120703010178N24

Enrollment

Registered

2021-04-09

Start date

2020-04-20

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemic stroke. ischemic stroke

Interventions

Intervention 1: Intervention group: Patients receiving 600000 international unit of intramuscular vitamin D in day 0. Intervention 2: Control group: Patients receiving standard treatment.

Eligibility

Sex/Gender

All

Age

16 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with Ischemic Stroke Patients over 16

Exclusion criteria

Exclusion criteria: Myocardial infarction in past 30 days Vitamin D level more than 30ng/ml

Design outcomes

Primary

Measure	Time frame
Changes in the neuron-specific enolase between two arms of the study. Timepoint: Before intervention and 3 days after intervention. Method of measurement: EIA kit for the measurement of neuron-specific enolase.	—

Secondary

Measure	Time frame
National Institutes of Health Stroke Scale. Timepoint: Daily until hospital discharge. Method of measurement: National Institutes of Health Stroke Scale questioner.;Barthel index. Timepoint: 3 months after stroke. Method of measurement: Barthel index questioner.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactOmid Hesami

Shahid Beheshti University of Medical Sciences

hesami.omid@yahoo.com+98 21 8820 0087

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026