Effect of vitamin D on duration of mechanical ventilation

Evaluation of vitamin D effect on duration of mechanical ventilation and Total Antioxidant Capacity (TAC) in ICU admitted patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120703010178N16

Enrollment

Registered

2018-06-25

Start date

2018-05-22

Completion date

Unknown

Last updated

2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanically ventilated patients in the intensive care unit. Diseases of the respiratory system

Interventions

Intervention 1: Intervention group: Receiving 300000 international unit of intramuscular vitamin D by DARUPAKHSH manufacture in day 0. Intervention 2: Control group: Patients receiving intramuscular p

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: ICU admitted patients equal or over 18 years old Mechanically ventilated patients Patients expected to be alive until 96 hours after ICU admission

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
25-Hydroxy vitamin D level. Timepoint: Day 0 and 7. Method of measurement: Blood 25-hydroxy vitamin D measurement.	—

Secondary

Measure	Time frame
Total Antioxidant Capacity (TAC) level. Timepoint: Day 0 and 7. Method of measurement: Total Antioxidant Capacity kit.;Duration of mechanical ventilation in intensive care unit. Timepoint: Daily. Method of measurement: Counting mechanical ventilator connection days.;Drug effect on rate of respiratory infection. Timepoint: Daily until 7 days and on day 14 and 28. Method of measurement: CPIS (Clinical Pulmonary Infection Score).;Mortality. Timepoint: Daily until 7 days and on day 14 and 28. Method of measurement: Sequential Organ Failure Assessment score.	—

Measure

Time frame

Total Antioxidant Capacity (TAC) level. Timepoint: Day 0 and 7. Method of measurement: Total Antioxidant Capacity kit.;Duration of mechanical ventilation in intensive care unit. Timepoint: Daily. Method of measurement: Counting mechanical ventilator connection days.;Drug effect on rate of respiratory infection. Timepoint: Daily until 7 days and on day 14 and 28. Method of measurement: CPIS (Clinical Pulmonary Infection Score).;Mortality. Timepoint: Daily until 7 days and on day 14 and 28. Method of measurement: Sequential Organ Failure Assessment score.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Sistanizad

Shahid Beheshti University of Medical Sciences

sistanizadm@sbmu.ac.ir+98 21 8820 0087

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026