Migraine. Migraine
Conditions
Interventions
Intervention 1: We randomly divided participants in 3 groups: cinnarizine group received one Cinnarizine tablet (37.5 mg for patients aged 6 to 11 and 50 mg for others aged 12 to 17) per day. All dru
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
6 Years to 17 Years
Inclusion criteria
Inclusion criteria: Patients with migraine (with or without aura), diagnosed according to the International Headache society criteria Patients who had at least four migraine attacks per 4 weeks; or sever dysfunction in daily and school activities during prospective baseline phase.
Exclusion criteria
Exclusion criteria: Chronic headache, complications of migraine or other migraine variant Children and adolescents with Focal neurologic deficit History of diagnosed sensitivity to each of drugs that used in the study Patients who took prophylactic therapy for migraine within 8 weeks before study. Headaches related to structural brain lesions Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of headache. Timepoint: frequency of frequency of each attack in a month. Method of measurement: questionnaire.;Intensity of headache. Timepoint: intensity of each attack. Method of measurement: Visual analogue scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects. Timepoint: in the double-blind phase of the study. Method of measurement: ask from participants and parents.;More than 50% responder rate. Timepoint: in the double-blind phase of the study and baseline. Method of measurement: ask from participants and parents. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahtab Ramezani
Tehran University of Medical Sciences
Outcome results
None listed