Local Anesthesia of Digital Nerve. Local anaesthetics
Conditions
Interventions
Treatment - Drugs
Intervention 1: Control group: 2 cc identical syringes contain 1cc Ketamine(=50mg) or 1cc distilled water prepared out of emergency department in blocks of 12. In control group 1 cc of distilled water
Placebo
Control group: 2 cc identical syringes contain 1cc Ketamine(=50mg) or 1cc distilled water prepared out of emergency department in blocks of 12. In control group 1 cc of distilled water will drop in on
Intervention group: 2 cc identical syringes contain 1cc Ketamine(=50mg) or 1cc distilled water prepared out of emergency department in blocks of 12. In intervention group 1 cc of Ketamine (=50 mg) wil
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Hand fingers trauma needed to digital nerve block for procedures; patients who signed the consent form Exclusion criteria: Age under 15; Can not communicate because of mental retardation; language barriers, loss of consciousness, intoxication or other causes; Pregnancy; Hemodynamic instability (systolic BP less than 90 or more than 180 mmHg); Chronic opium user or use any of sedative-analgesic in last 12 hours; Known reactive or anatomic airway diseases; Decompensated heart failure or acute coronary syndrome (based on History and physical exam OR documentations) ; Known allergy to Ketamine or Lidocaine.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain of injured finger. Timepoint: entrance, after instillation of drug or placebo (pre-procedural pain), after completion of procedure (post-procedure pain). Method of measurement: Numeric Rating Scale (NRS) 10 part.;Complication of control or placebo drug. Timepoint: continouesly from initial instillation of drug until 30 min after procedure. Method of measurement: Ketamine complication such as Hallucination, Nausea, vomiting, hypertension, agitation and seizure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart Rate. Timepoint: Before instilation and 30 min after that. Method of measurement: By pulse-oxymeter or Cardiac monitor.;Systolic BP. Timepoint: Before instilation and 30 min after that. Method of measurement: Sphygmomanometer.;Arterial O2 Saturation. Timepoint: Before instilation and 30 min after that. Method of measurement: By pulse-oxymeter.;Procedure complication. Timepoint: Begining of procedure until 30 min after that. Method of measurement: Hematoma, Bleeding, Ischemia, . | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Nejati M.D.
Tehran University of Medical Sciences
Outcome results
None listed