The effect of hypothyroidism treatment with levothyroxine on improvement of benign breast disorders

Assessment of the effect of hypothyroidism treatment with levothyroxine on the improvement of benign breast disorders in women attending the breast clinic of Arash Womens Hospital.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201206264329N3

Enrollment

Registered

2012-08-30

Start date

2012-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Fibrocystic mastopathy. Condition 2: Mastodynia. Condition 3: Nipple discharge. Diffuse cystic mastopathy Mastodynia Other signs and symptoms in breast/nipple discharge

Interventions

Intervention 1: there is no intervention in the control group. Intervention 2: intervention in the case group is administration of tablet levothyroxine with 50 Micrograms initial dose , for 3 months.

Treatment - Drugs

there is no intervention in the control group.

intervention in the case group is administration of tablet levothyroxine with 50 Micrograms initial dose , for 3 months

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women with fibrocystic disease;Mild and moderate mastalgia ; nipple discharge : Inclusion criteria. The patient considered for surgical intervention; Pregnant women ; Women taking oral contraception pill ;history of breast cancer ;High levels of Prolactin ;History of hyperthyroidism or hypothyroidism: Exclusion criteria

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Intensity of benign breast disorders. Timepoint: Befor and 3 months after intervention. Method of measurement: Clinical exam.Ultrasound .Visual Analog Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSadaf Alipour

Tehran University of Medical Sciences

salipour@sina.tums.ac.ir+98 21 7771 9922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026