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Comparing three drugs, apotel, oxycodone and acetaminophen codeine analgesia after nasal surgery

A comparison of analgesic effect of Intravenous Acetaminophen (Apotel) versus Oxycodone Tablet and oral Acetaminophen codeine in Rhinoplasty and Septoplasty Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012062410102N1
Enrollment
75
Registered
2012-12-24
Start date
2011-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

control of post operative pain. Analgesics, antipyretics and anti-inflammatory drugs

Interventions

Intervention 1: Tab Acetaminophen Codeine 310 mg 2 Tab every 6 hours for 24 hours. Intervention 2: Tab oxycodone 5 mg 2 Tab every 8 hours for 24 hours. Intervention 3: Amp apotel 1000 mg 1 Amp every 8
Treatment - Drugs
Tab Acetaminophen Codeine 310 mg 2 Tab every 6 hours for 24 hours
Tab oxycodone 5 mg 2 Tab every 8 hours for 24 hours
Amp apotel 1000 mg 1 Amp every 8 hours for 24 hours

Sponsors

Vice chancellor for research Tehran University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 18-40 years; Elective patient for septorhinoplasty sergury; Postoperative pain; Anesthesia without complication. exclusion criteria: Any alergic history with acetaminophen; oxycodone, and codeine; Contraindication for opioids; severe pain with high VAS score; Renal disease with Cr >1.5; Liver disease with LFT >1.5 times; Lung disease ; Coagulopathy ; Pregnancy and lactation; Asthma; Unstable hemodynamic; Anti epileptic agents

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: every 4 hours. Method of measurement: VAS scaling.

Secondary

MeasureTime frame
Nausa and vomiting. Timepoint: every 4 hours. Method of measurement: asking.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEhsan Bastanhagh

Tehran University of Medical Sciences

e-bastanhagh@razi.tums.ac.ir+98 21 6435 2326

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026