The effect of intrauterine administration of human chorionic gonadotropin after oocyte pick up on the outcome of intracytoplasmic sperm injection and embryo transfer (ICSI/ET) in infertile couples

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201206165485N4

Enrollment

Registered

2015-09-02

Start date

2014-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. Female infertility

Interventions

Intervention 1: Intervention group 1: immediately after oocyte pick up, the patients in the study group will receive intrauterine 500 unit of human chorionic gonadotropin (HSG) with trade mark of Chor

Treatment - Drugs

Intervention group 1: immediately after oocyte pick up, the patients in the study group will receive intrauterine 500 unit of human chorionic gonadotropin (HSG) with trade mark of Choriomon (IBSA) in

Control group: Immediately after oocyte pick up, the patients in the control group will receive 0.5 cc of normal saline through cervical canal after passing the internal os, by intrauterine inseminat

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Eighteen to forty years old women candidate of intracytoplasmic sperm injection and embryo transfer (ICSI/ET); normal TSH; normal PRL; normal AMH or day 2 to 4 FSH and E2 Exclusion criteria: Uncontrolled chronic maternal disease like endocrinopathy and autoimmune disease; endometriosis; severe hydrosalpinx; azospermia; oocyte donation; when it is required to do a surgical operation after oocyte pick up and before embryo transfer or for any reason the embryo transfer must be deferred; high risk of OHSS; morphologic embryo deficiencies

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Implantation rate. Timepoint: two weeks after embryo transfer. Method of measurement: beta HCG titrating.;Pregnancy rate. Timepoint: 3weeks after embryo transfer. Method of measurement: ultrasonography.;Heart rate detection. Timepoint: 4weeks after embryo transfer. Method of measurement: ultrasonography.	—

Secondary

Measure	Time frame
Ectopic pregnancy rate, abortion rate. Timepoint: four weeks after embryo transfer. Method of measurement: beta HCG titrating, ultrasonography.;Ovarian hyperstimulation rate. Timepoint: 1week after transfer. Method of measurement: sign and symptoms.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazli Navali

Tabriz University of Medical Sciences

navalin@tbzmed.ac.ir+98 41 3554 1221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 12, 2026