Evaluation of the relationship between NCPAP use and chronic lung disease in preterm infants.

Evaluation of the relationship between isolation from NCPAP at 3 and 5 cm H2O pressures with the incidence of BPD in neonates admitted to the NICU ward with a gestational age less than or equal to 32 weeks and birth weight less than or equal to 1500 grams.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120614010026N11

Enrollment

206

Registered

2022-03-13

Start date

2022-01-21

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchopulmonary dysplasia.

Interventions

Intervention 1: In infants in the intervention group who are under CPAP (Continuous Positive Airway Pressure) if the clinical condition is stable at 5CmH2O, the CPAP pressure is reduced by one every 1

Eligibility

Sex/Gender

All

Age

1 Days to 28 Days

Inclusion criteria

Inclusion criteria: All preterm infants less than or equal to 32 weeks of gestation and weighing less than or equal to 1500 g receiving NCPAP for at least 24 hours immediately after birth with a diagnosis of RDS.

Exclusion criteria

Exclusion criteria: Congenital heart disease, Third and fourth degree intraventricular hemorrhage, Need surgery Major anomalies Need to be sent to other medical centers Receive NCPAP in less than 24 hours Apgar score less than 4 in 5 minutes of birth Asphyxia, Having Craniofacial abnormalities

Design outcomes

Primary

Measure	Time frame
Rate of Bronchopulmonary Dysplasia. Timepoint: 28th birthday. Method of measurement: daily recorded sheet.	—

Secondary

Measure	Time frame
Frequency distribution of pneumothorax. Timepoint: At the time of discharge from the hospital. Method of measurement: Using a questionnaire and daily recorded sheet.;Frequency distribution of intraventricular hemorrhage(IVH). Timepoint: At the time of discharge from the hospital. Method of measurement: Using brain ultrasound.;Frequency distribution of Patent ductus arteriosus (PDA). Timepoint: At the time of discharge from the hospital. Method of measurement: Using echocardiography.;Duration of oxygen dependence. Timepoint: At the time of discharge from the hospital. Method of measurement: Using a questionnaire and daily recorded sheet.;Time to reach full enteral nutrition. Timepoint: At the time of discharge from the hospital. Method of measurement: Using a questionnaire and daily recorded sheet.;Duration of hospitalization. Timepoint: At the time of discharge from the hospital. Method of measurement: Using a questionnaire and daily recorded sheet.	—

Measure

Time frame

Frequency distribution of pneumothorax. Timepoint: At the time of discharge from the hospital. Method of measurement: Using a questionnaire and daily recorded sheet.;Frequency distribution of intraventricular hemorrhage(IVH). Timepoint: At the time of discharge from the hospital. Method of measurement: Using brain ultrasound.;Frequency distribution of Patent ductus arteriosus (PDA). Timepoint: At the time of discharge from the hospital. Method of measurement: Using echocardiography.;Duration of oxygen dependence. Timepoint: At the time of discharge from the hospital. Method of measurement: Using a questionnaire and daily recorded sheet.;Time to reach full enteral nutrition. Timepoint: At the time of discharge from the hospital. Method of measurement: Using a questionnaire and daily recorded sheet.;Duration of hospitalization. Timepoint: At the time of discharge from the hospital. Method of measurement: Using a questionnaire and daily recorded sheet.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Amir Mohammad Armanian

Esfahan University of Medical Sciences

armanian@med.mui.ac.ir+98 31 3668 8597

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026